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THE AUTONOMOUS BEHAVIOUR OF NORMAL THYMUS GRAFTS
Author(s) -
Metcalf Donald
Publication year - 1963
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1963.64
Subject(s) - medullary cavity , biology , lymphatic system , anatomy , pathology , medicine , immunology
SUMMARY The growth of individual thymus grafts in isologous mice was unaffected by the presence of as many as twenty‐three other thymus grafts in the same host animal. The lymphoid organs of mice bearing multiple thymus grafts showed little deviation from normal. Thymus fragments, as small as 0·5 mg., were successfully grafted, but all successful grafts contained medullary tissue. The percentage of medullary tissue in all types of thymus grafts was constant and the size attained by a thymus graft appeared to be determined by the size of the surviving medullary tissue from the original graft.