Premium
THE LOCALISATION OF THE INFLUENCE OF CROTON OIL STIMULATION ON TUMOUR INITIATION BY URETHANE IN MICE
Author(s) -
Pound Allan W
Publication year - 1963
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1963.6
Subject(s) - croton oil , croton , acetone , stimulation , medicine , anesthesia , chemistry , traditional medicine , organic chemistry , inflammation
SUMMARY Groups of mice were painted with a solution of croton oil in acetone on one‐half of the skin of the back twenty‐four hours prior to an injection of urethane. The whole skin of the back was subsequently painted with croton oil weekly for twenty weeks. The number of papillomata developed on the skin was greater on the half given the preliminary application of croton oil. The augmented tumour yield is accounted for by local phenomena produced by the preliminary application of croton oil.