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THE EFFECT OF TRAUMATIC SHOCK ON EXPERIMENTAL BLOOD ETHYL ALCOHOL LEVELS IN MICE
Author(s) -
Lykke AWJ,
Robertson JS,
Kosche ER
Publication year - 1963
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1963.27
Subject(s) - alcohol , intraperitoneal injection , ethanol , blood alcohol , medicine , anesthesia , shock (circulatory) , poison control , chemistry , injury prevention , biochemistry , emergency medicine
SUMMARY In a controlled experiment using 86 pairs of male white mice matched for weight, the blood alcohol level after intraperitoneal injection of ethyl alcohol was slightly but significantly elevated in animals in which a closed fracture of the femur was produced at the time of the alcohol injection. Significant elevation of blood alcohol was present at half an hour after alcohol injection and was still present three hours after injection. Blood alcohol levels in both injured and control animals decreased linearly at the same rate with the logarithm of time, but the regression line of the blood alcohol levels of the injured animals was higher than that of the control animals.