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RADIATION INDUCED “ACCEPTANCE” AND THE IMMATURE HAEMOPOIETIC HOMOGRAFT
Author(s) -
Ilbery PLT
Publication year - 1960
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1960.8
Subject(s) - transplantation , homologous chromosome , lethal dose , embryonic stem cell , biology , grafting , whole body irradiation , foreign body , immunology , medicine , toxicology , chemistry , surgery , genetics , organic chemistry , gene , polymer
SUMMARY Following lethal whole body irradiation and homologous embryonic haemopoietic grafting, transplantation of the matured grafted material was made into further lethally irradiated test animals with the object of demonstrating tolerance. This has been judged by the ability of such transplanted material to avoid secondary disease in a foreign host environment.