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CHANGES IN POLARISATION RESISTANCE DURING THE REPOLARISATION PHASE OF THE RABBIT VENTRICULAR ACTION POTENTIAL
Author(s) -
Johnson EA,
Tille J
Publication year - 1960
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1960.56
Subject(s) - microelectrode , cardiology , resting potential , intracellular , ventricular action potential , medicine , materials science , biophysics , electrophysiology , chemistry , biology , repolarization , electrode , biochemistry
SUMMARY The magnitude and time course of changes in polarisation resistance during the repolarisation phase of action potentials recorded from rabbit ventricular muscle have been measured with intracellular double‐barrelled microelectrodes. Action potentials from 74 fibres in 7 preparations have been examined. In all fibres, at some time during the repolarisation phase, the polarisation resistance was greater than the resting polarisation resistance. The mean maximum increase above the resting value was 1·63 (± 0·15 S.D.) times. The polarisation resistance remained constant even with large negative voltage displacements (60 mV). No evidence was found of regenerative repolarisation.