Open AccessEffects of mutation at arginine-218 residue on the reaction of synthetic thymidylate synthase and 5-fluorouracil
Author(s) -
SungWoo Cho,
Jong Weon Lee,
Eun Hee Cho
Publication year - 1996
Publication title -
experimental and molecular medicine/experimental and molecular medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.703
H-Index - 82
eISSN - 2092-6413
pISSN - 1226-3613
DOI - 10.1038/emm.1996.12
Subject(s) - thymidylate synthase , complementation , mutant , phenylglyoxal , enzyme kinetics , biochemistry , lactobacillus casei , mutagenesis , chemistry , enzyme , biology , arginine , microbiology and biotechnology , active site , amino acid , gene , genetics , fermentation , fluorouracil , chemotherapy