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Ncking BCR‐mediated PI3K activation
Author(s) -
Cans Jennifer L,
Zhao Fang,
Schwartzberg Pamela L
Publication year - 2013
Publication title -
embo reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.584
H-Index - 184
eISSN - 1469-3178
pISSN - 1469-221X
DOI - 10.1038/embor.2013.133
Subject(s) - regulator , breakpoint cluster region , pi3k/akt/mtor pathway , microbiology and biotechnology , negative regulator , signal transduction , cancer research , biology , chemistry , receptor , genetics , gene
Nck has been recently shown to be a crucial regulator of B cell receptor (BCR) signaling and link it to PI3K pathways. Notably, this is independent from the known role of Nck in actin reorganization.