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Autophagy—alias self‐eating—appetite and ageing
Author(s) -
Rubinsztein David C
Publication year - 2012
Publication title -
embo reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.584
H-Index - 184
eISSN - 1469-3178
pISSN - 1469-221X
DOI - 10.1038/embor.2012.5
Subject(s) - autophagy , appetite , neuropeptide y receptor , endocrinology , obesity , neuropeptide , ageing , biology , medicine , neuroscience , biochemistry , apoptosis , receptor
Two articles—one published online in January and in the March issue EMBO reports —implicate autophagy in the control of appetite by regulating neuropeptide production in hypothalamic neurons. Autophagy decline with age in POMC neurons induces obesity and metabolic syndrome.