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Stemness as a cell default state
Author(s) -
Casanova Jordi
Publication year - 2012
Publication title -
embo reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.584
H-Index - 184
eISSN - 1469-3178
pISSN - 1469-221X
DOI - 10.1038/embor.2012.47
Subject(s) - stem cell , microbiology and biotechnology , cellular differentiation , cell fate determination , state (computer science) , biology , cell , business , transcription factor , genetics , computer science , gene , algorithm
Could it be that stemness is not a specific fate resulting from a distinct stem‐cell programme, but simply a result of a stem cell escaping ulterior differentiation? Stemness could be entirely intrinsic to non‐differentiated cells.