Premium
Get your fingers out of p53's way!
Author(s) -
Bublik Débora Rosa,
Oren Moshe
Publication year - 2012
Publication title -
embo reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.584
H-Index - 184
eISSN - 1469-3178
pISSN - 1469-221X
DOI - 10.1038/embor.2012.33
Subject(s) - p53 protein , apoptosis , biology , microbiology and biotechnology , gene , programmed cell death , genetics
Premature triggering of cell death by p53 has to be avoided. A recent study in EMBO reports demonstrates how the anti‐apoptotic protein Apak represses the expression of the pro‐apoptotic p53 target gene p53AIP1 in non‐stressed cells.