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Telomere flip‐flop: an unfolding passage to senescence
Author(s) -
Price Carolyn M
Publication year - 2012
Publication title -
embo reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.584
H-Index - 184
eISSN - 1469-3178
pISSN - 1469-221X
DOI - 10.1038/embor.2011.237
Subject(s) - telomere , genome instability , senescence , limiting , biology , suppressor , genetics , microbiology and biotechnology , function (biology) , telomerase , cellular senescence , promoter , computational biology , dna , dna damage , gene , phenotype , gene expression , mechanical engineering , engineering
In this issue of EMBO reports , insight is provided into how telomeres can function both as tumour suppressors by limiting the number of times a cell can divide and as tumour promoters by allowing genomic instability.