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E‐cadherin, a new mixer in the Yamanaka cocktail
Author(s) -
Lowry William E
Publication year - 2011
Publication title -
embo reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.584
H-Index - 184
eISSN - 1469-3178
pISSN - 1469-221X
DOI - 10.1038/embor.2011.117
Subject(s) - klf4 , reprogramming , cadherin , sox2 , microbiology and biotechnology , biology , genetics , transcription factor , cell , gene
A paper published in May in EMBO reports by Redmer et al demonstrates that expression of E‐cadherin together with three of the Yamanaka factors (Sox2, Klf4 and c‐Myc) induces reprogramming of murine fibroblasts, even in the absence of Oct4.