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Second meiotic arrest and exit in frogs and mice
Author(s) -
Perry Anthony C.F.,
Verlhac MarieHélène
Publication year - 2008
Publication title -
embo reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.584
H-Index - 184
eISSN - 1469-3178
pISSN - 1469-221X
DOI - 10.1038/embor.2008.22
Subject(s) - xenopus , meiosis , microbiology and biotechnology , biology , vertebrate , cell cycle checkpoint , human fertilization , embryonic stem cell , genetics , cell cycle , cell , gene
Mature vertebrate oocytes typically undergo programmed arrest at the second meiotic cell cycle until they are signalled to initiate embryonic development at fertilization. Here, we describe the underlying molecular mechanisms of this second meiotic arrest and release in Xenopus , and compare and contrast them with their counterparts in mice.