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Struggling to let go: a non‐coding RNA directs its own extension and destruction
Author(s) -
Bernecky Carrie,
Cramer Patrick
Publication year - 2013
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2013.36
Subject(s) - biology , extension (predicate logic) , rna , genetics , coding (social sciences) , non coding rna , computational biology , gene , computer science , statistics , mathematics , programming language
A mammalian non‐coding RNA (ncRNA) templates its extension by Pol II, leading to its destabilization. This represents the first RNA‐dependent RNA polymerase (RdRP) activity in higher organisms.