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Early replication fragile sites: where replication–transcription collisions cause genetic instability
Author(s) -
Mortusewicz Oliver,
Herr Patrick,
Helleday Thomas
Publication year - 2013
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2013.20
Subject(s) - dna replication , chemical biology , biology , genetics , dna
Groundbreaking work reported by Barlow et al in Cell identifies a new class of fragile sites as a source of genomic rearrangements in cancer.