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The Yin and Yang of enhancer‐like RNAs
Author(s) -
Shiekhattar Ramin
Publication year - 2013
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2013.185
Subject(s) - biology , enhancer , long non coding rna , non coding rna , transcription (linguistics) , rna , transcription factor , small nucleolar rna , enhancer rnas , regulation of gene expression , genetics , gene , computational biology , linguistics , philosophy
The transcription factor YY1 inhibits myogenesis by inducing the long intergenic noncoding RNA Yam‐1, which in turn activates miRNA‐715 expression in cis, a finding that expands the regulatory potential of lincRNAs.
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