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CRISPRs extending their reach: prokaryotic RNAi protein Cas9 recruited for gene regulation
Author(s) -
Heidrich Nadja,
Vogel Jörg
Publication year - 2013
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2013.141
Subject(s) - biology , crispr , rna interference , gene , genetics , cas9 , computational biology , rna
CRISPR systems not only defend bacteria from foreign DNA but also contribute to pathogenicity, by regulating endogenous gene expression to evade host innate immune responses.