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Lateral thinking: CaMKII uncouples kainate receptors from mossy fibre synapses
Author(s) -
Copits Bryan A,
Swanson Geoffrey T
Publication year - 2013
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2013.12
Subject(s) - neuroscience , postsynaptic potential , excitatory postsynaptic potential , synapse , biology , receptor , genetics , inhibitory postsynaptic potential
Activation of CaMKII induces long‐term depression at the hippocampal mossy fibre synapse by promoting lateral diffusion of kainate receptors out of the synapse to fine‐tune synaptic plasticity.