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The many functions of cohesin—different rings to rule them all?
Author(s) -
Peters JanMichael
Publication year - 2012
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2012.90
Subject(s) - cohesin , biology , establishment of sister chromatid cohesion , sister chromatids , sister , genetics , dna , chromosome , gene , chromatin , sociology , anthropology
Two studies generating and characterizing mice that lack the core cohesin subunit SA1reveal its essential roles in telomere replication and gene expression, which cannotbe taken over by cohesin complexes containing the paralog SA2.