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Human mitotic chromosome structure: what happened to the 30‐nm fibre?
Author(s) -
Hansen Jeffrey C
Publication year - 2012
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2012.66
Subject(s) - biology , chromatin , mitosis , chromosome , premature chromosome condensation , dna , genetics , gene
After decades of pursuit of the structure and properties of higher‐order chromatin structures, new work shows that regular 30‐nm fibres are absent from human mitotic chromosomes, with chromosome‐level condensation achieved instead by packaging of 10‐nm fibres in a fractal manner.