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B‐type lamins and their elusive roles in metazoan cell proliferation and senescence
Author(s) -
Hutchison Christopher J
Publication year - 2012
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2012.39
Subject(s) - biology , microbiology and biotechnology , senescence , lamin , cell growth , genetics , nucleus
Recent papers question the traditional role of B‐type lamins in DNA replication and transcription, but highlight an entirely novel yet fundamental role for lamin B1 in cell proliferation and cellular senescence.