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AgRP neurons: a switch between peripheral carbohydrate and lipid utilization
Author(s) -
Varela Luis,
Horvath Tamas L
Publication year - 2012
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2012.287
Subject(s) - biology , carbohydrate , neuroscience , biochemistry
AgRP/NPY neurons are critical regulators of body weight and food intake. Unexpectedly, AgRP‐ablated mice show an obese phenotype, which is linked to altered metabolism in liver, muscle and pancreas.