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Low‐hanging fruit: targeting Brdt in the testes
Author(s) -
Bryant Jessica M,
Berger Shelley L
Publication year - 2012
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2012.259
Subject(s) - biology , epigenetics , genetics , developmental biology , gene
Brdt, a testes‐specific BET family chromatin reader, regulates sperm development. Pharmacological inhibition of Brdt provides an approach for reversible male contraception.