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Che‐ating death: CHE1/AATF protects from p53‐mediated apoptosis
Author(s) -
Jackson James G,
Lozano Guillermina
Publication year - 2012
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2012.258
Subject(s) - biology , apoptosis , programmed cell death , genetics , microbiology and biotechnology , cancer research
Depending on the context, the tumour suppressor p53 directs cells either to apoptosis or to cell‐cycle arrest/senescence, with implications for ageing and cancer. The RNA PolII binding protein CHE1/AATF governs this choice.
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