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NURDs are required for diversity
Author(s) -
Fazzio Thomas G,
Rando Oliver J
Publication year - 2012
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2012.137
Subject(s) - medical school , library science , function (biology) , diversity (politics) , gerontology , medicine , biology , medical education , genetics , law , computer science , political science
NURD was recently shown to functionally recruit PRC2 to a set of common target genes. A new study in Cell Stem Cell reveals a crucial role for NURD in embryonic stem cell lineage commitment by regulating the transcriptional heterogeneity of pluripotency factors.