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Direct conversion in the heart: a simple twist of fate
Author(s) -
DeWitt Natalie D,
Trounson Alan
Publication year - 2012
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2012.114
Subject(s) - biology , simple (philosophy) , twist , geometry , mathematics , epistemology , philosophy
Direct injection of reprogramming transcription factors into infarcted hearts of mice transforms cardiac fibroblast into functional cardiomyocytes providing crucial support for in‐vivo transdifferentiation as alternative route for tissue regeneration.

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