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SUMO unloads the Kap114 cab
Author(s) -
Werner Andreas,
Melchior Frauke
Publication year - 2012
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2012.103
Subject(s) - biology , computational biology
Translocation of proteins across the nuclear pore complex depends on transport receptors and the GTPase Ran. SUMO conjugation of an importin β‐like transport receptor by the conjugating enzyme Mms21 stimulates the intranuclear release of cargo from the transport protein karyopherin.