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Myosin drives autophagy in a pathway linking Atg1 to Atg9
Author(s) -
Bialik Shani,
Pietrokovski Shmuel,
Kimchi Adi
Publication year - 2011
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2011.8
Subject(s) - biology , autophagy , myosin , microbiology and biotechnology , genetics , apoptosis
The Atg1 kinase promotes autophagy, but its substrates have remained elusive. In this issue of the EMBO Journal , Tang et al identify a myosin light chain kinase as an Atg1 substrate, revealing a pathway that regulates Atg9 trafficking and autophagosome formation.