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Genomic instability in iPS: time for a break
Author(s) -
Blasco Maria A,
Serrano Manuel,
FernandezCapetillo Oscar
Publication year - 2011
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2011.50
Subject(s) - biology , genome instability , instability , computational biology , genetics , evolutionary biology , dna , dna damage , physics , mechanics
This ‘Have you seen?’ features important insights into genomic aberrations of pluripotent stem cells from studies recently published in Nature , Cell Stem Cell and Cell Death & Differentiation . These findings highlight necessary caution before translating this technology into actual therapies.