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Ubiquitin‐mediated regulation of RhoGTPase signalling: IAPs and HACE1 enter the fray
Author(s) -
Orme Mariam,
Bianchi Katiuscia,
Meier Pascal
Publication year - 2012
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2011.452
Subject(s) - biology , microbiology and biotechnology , ubiquitin , ubiquitin ligase , ubiquitin protein ligases , biochemistry , gene
Two recent studies, including one EMBO Journal article, add ubiquitination by the distinct IAP and HACE1 ubiquitin ligases to the complex network regulating the multiple cellular activities of Rac1.