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G4 DNA: at risk in the genome
Author(s) -
Davis Luther,
Maizels Nancy
Publication year - 2011
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2011.342
Subject(s) - biology , genome , genetics , dna , computational biology , evolutionary biology , gene
A study in this issue offers new evidence for G‐quadruplex (G4) DNA structure formation in vivo and its contribution to genomic instability, and identifies specific cellular mechanisms to cope with such threats.