Premium
Arp you ready for actin in the nucleus?
Author(s) -
Kast David J,
Dominguez Roberto
Publication year - 2011
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2011.150
Subject(s) - biology , library science , computer science
Actin and actin‐related proteins (Arps) have crucial yet little understood roles as components of chromatin‐remodelling complexes. A study in this issue of The EMBO Journal reports the first structural investigation of two nuclear Arps, the INO80 complex subunits Arp4 and Arp8, and sheds light on the critical role that the nucleotide state of actin may have on its interactions with the Arps.