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Somatic piRNA biogenesis
Author(s) -
Zamore Phillip D
Publication year - 2010
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2010.232
Subject(s) - piwi interacting rna , biology , rasirna , rna interference , somatic cell , transposable element , microrna , biogenesis , small rna , genetics , rna , gene , genome
PIWI‐interacting RNAs (piRNAs) play an important role in silencing transposons within the germline; how they are generated and how they exert their silencing function is not well understood. Here Phil Zamore highlights recent work from the Brennecke lab that provides new insight into the factors involved in these small RNA biogenesis pathways.