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MEK signalling tunes actin treadmilling for interstitial lymphocyte migration
Author(s) -
Weber Michele,
Sixt Michael
Publication year - 2010
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2010.183
Subject(s) - biology , actin , immunology , microbiology and biotechnology
Lymphocytes must undergo various modes of migration during an immune response, depending on the underlying substrate. The identification of a signalling module required specifically for 3D motility sheds light onto how these different migratory mechanisms can be regulated.