Premium
Dispose to the pole—protein aggregation control in bacteria
Author(s) -
Ziętkiewicz Szymon,
Liberek Krzysztof
Publication year - 2010
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2010.12
Subject(s) - biology , bacteria , dispose pattern , bacterial protein , escherichia coli proteins , genetics , computer science , programming language
The disaggregation and refolding of polypeptides aggregated in bacterial cells in response to environmental stress is crucial for the development of thermotolerance. Although the mechanistic aspects of the chaperone‐dependent disaggregation reaction are known, the spatio‐temporal organization of this process is less understood. In this issue, Winkler et al (2010) present the results of technically advanced studies on the organization of this process and its biological consequences in bacterial cells.