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Dendritic tiling through TOR signalling
Author(s) -
Hong Weizhe,
Luo Liqun
Publication year - 2009
Publication title -
the embo journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.484
H-Index - 392
eISSN - 1460-2075
pISSN - 0261-4189
DOI - 10.1038/emboj.2009.353
Subject(s) - biology , library science , art history , computer science , art
In many sensory systems, dendrites of sensory neurons cover an entire sensory field in a complete and non‐redundant manner, a phenomenon called dendritic tiling. Previous studies have identified the Tricornered (Trc) kinase as an important regulator of this process. In this issue of The EMBO Journal , Koike‐Kumagai et al (2009) found that the target of rapamycin (TOR) complex 2 (TORC2) is essential for dendritic tiling by way of regulating Trc kinase activity in Drosophila class IV dendritic arborization (da) neurons. This study provides the first in vivo evidence for a function of TORC2 activity in nervous system development.