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Prioritized Current Unmet Needs for Antibacterial Therapies
Author(s) -
Spellberg B,
Shlaes D
Publication year - 2014
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.2014.106
Subject(s) - intensive care medicine , medicine , antibiotic resistance , antibiotics , biology , microbiology and biotechnology
As a result of declining new antibacterial approvals and rising antibiotic resistance, society clearly needs new treatments for bacterial infections. Specific areas of unmet need evolve over time owing to changes in resistance patterns and treatment strategies. Our goal here is to describe and prioritize the current areas of greatest unmet need for new antibacterial development based on an understanding of the most serious treatment challenges facing patients and their providers today. Clinical Pharmacology & Therapeutics (2014); 96 2, 151–153. doi: 10.1038/clpt.2014.106