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Pharmacological Treatment of Acute Heart Failure: Current Treatment and New Targets
Author(s) -
Pöss J,
Link A,
Böhm M
Publication year - 2013
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.2013.136
Subject(s) - medicine , heart failure , clinical pharmacology , intensive care medicine , clinical trial , pharmacology
Acute heart failure (AHF) is defined as the rapid onset of, or changes in, the symptoms and signs of heart failure (HF). It is a life‐threatening situation in which diagnosis and initiation of therapy are crucial. The treatment aims are to stabilize the patient, improve clinical symptoms, and increase long‐term survival rates. Few treatments have been investigated in clinical trials. This review summarizes the principles of pharmacologic treatment, the underlying clinical trials, and new pharmacologic targets. Clinical Pharmacology & Therapeutics (2013); 94 4, 499–508. doi: 10.1038/clpt.2013.136