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The UCSF‐FDA TransPortal: A Public Drug Transporter Database
Author(s) -
Morrissey K M,
Wen C C,
Johns S J,
Zhang L,
Huang SM,
Giacomini K M
Publication year - 2012
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.2012.44
Subject(s) - drug , resource (disambiguation) , transporter , computer science , pharmacology , medicine , chemistry , computer network , biochemistry , gene
Drug transporters play a key role in the absorption, distribution, and elimination of many drugs, and they appear to be important determinants of therapeutic and adverse drug activities. Although a large body of data pertaining to drug transporters is available, there are few databases that inform drug developers, regulatory agencies, and academic scientists about transporters that are important in drug action and disposition. In this article, we inform the scientific community about the UCSF‐FDA TransPortal, a new and valuable online resource for research and drug development. Clinical Pharmacology & Therapeutics (2012); 92 5, 545–546. doi: 10.1038/clpt.2012.44