Needs for an Expanded Ontology‐Based Classification of Adverse Drug Reactions and Related Mechanisms | Zendy

Zhichkin P E | Zendy; Athey B D | Zendy; Avigan M I | Zendy; Abernethy D R | Zendy

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Needs for an Expanded Ontology‐Based Classification of Adverse Drug Reactions and Related Mechanisms

Author(s) -

Zhichkin P E,

Athey B D,

Avigan M I,

Abernethy D R

Publication year - 2012

Publication title -

clinical pharmacology and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.941

H-Index - 188

eISSN - 1532-6535

pISSN - 0009-9236

DOI - 10.1038/clpt.2012.41

Subject(s) - ontology , clinical pharmacology , drug reaction , vocabulary , drug , computer science , adverse drug reaction , adverse effect , medicine , pharmacology , data science , epistemology , philosophy , linguistics

The growing significance of bioinformatics and systems biology in drug safety research requires a system of adverse‐event classification that goes beyond a simple vocabulary. This opinion piece outlines the need for development of an ontology‐based framework of describing adverse drug reactions (ADRs) and describes the potential applications for such a framework. Clinical Pharmacology & Therapeutics (2012); 91 6, 963–965. doi: 10.1038/clpt.2012.41

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