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Off‐Label Drug Use in Pediatric Patients
Author(s) -
Kimland E,
Odlind V
Publication year - 2012
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.2012.26
Subject(s) - agency (philosophy) , citation , clinical pharmacology , medicine , library science , computer science , pharmacology , sociology , social science
Until recently, it was considered unethical or impossible to perform clinical trials of new medicines in children. As a consequence, many medicines used for treating children are insufficiently documented with regard to dosing, efficacy, and safety. The off-label use of drugs has been extensive in treating the pediatric population. This article gives an overview of the extent and types of off-label use of medicines in pediatric populations.