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Achieving the Promise of Personalized Medicine
Author(s) -
Reynolds K S
Publication year - 2012
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.2012.147
Subject(s) - pharmacogenomics , clinical pharmacology , personalized medicine , precision medicine , intervention (counseling) , medicine , clinical practice , alternative medicine , pharmacology , bioinformatics , family medicine , nursing , biology , pathology
Individualized therapy is the practice of tailoring therapeutic intervention to a patient's disease, demographic characteristics, genetics, environment, lifestyle, and health status. In addition to previous methods of individualization, individualization based on pharmacogenomics is an emerging practice. Although tools are available to aid the determination of the need to individualize therapy, there are barriers to implementation. Various institutions have instituted programs to demonstrate the benefit of individualization, including programs that involve preemptive genotyping. Clinical Pharmacology & Therapeutics (2012); 92 4, 401–405. doi: 10.1038/clpt.2012.147