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Gastrohepatology: Tools, Targets, and Trajectories
Author(s) -
James L P,
Senior J
Publication year - 2012
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.2012.123
Subject(s) - clinical pharmacology , medicine , alimentary tract , medical prescription , intensive care medicine , drug , pharmacology
Gastrointestinal (GI) and hepatic conditions are a leading source of health‐care utilization today. A significant segment of the over‐the‐counter and prescription drug market comprises drugs used to alleviate symptoms localized to the alimentary tract. The discovery of new mechanisms of disease pathogenesis will inform the future development of targeted therapeutics for conditions managed by gastroenterologists and hepatologists. Newly approved drugs and evolving mechanistic targets offer a promising trajectory to both clinicians and patients with GI and liver disorders. Clinical Pharmacology & Therapeutics (2012); 92 3, 267–271. doi: 10.1038/clpt.2012.123