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Developing a Valid Patient‐Reported Outcome Measure
Author(s) -
Rothrock N E,
Kaiser K A,
Cella D
Publication year - 2011
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.2011.195
Subject(s) - clinical pharmacology , measure (data warehouse) , patient reported outcome , medical physics , quality (philosophy) , outcome (game theory) , clinical trial , health care , process (computing) , psychology , medicine , medical education , computer science , quality of life (healthcare) , nursing , data mining , pharmacology , mathematics , philosophy , mathematical economics , epistemology , economics , economic growth , operating system
Many aspects of patients' experiences with illness, medication, and health care are best captured from patient‐reported outcomes (PROs). In this article, we describe the process for constructing quality PRO instruments, from conceptual model development through instrument validation. We also discuss PROs as clinical trial end points and the potential of PRO data for aiding clinicians and patients in choosing from among multiple therapeutic options. Finally, we provide an overview of some existing PRO instruments. Clinical Pharmacology & Therapeutics (2011); 90 5, 737–742. doi: 10.1038/clpt.2011.195

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