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Age‐Reversing Drugs and Devices in Dermatology
Author(s) -
Sachs D L,
Voorhees J J
Publication year - 2011
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.2010.259
Subject(s) - photoaging , clinical pharmacology , skin aging , reversing , medicine , beauty , pharmacology , dermatology , philosophy , materials science , epistemology , composite material
The quest for youth and beauty is an ongoing one. No organ conveys youth and beauty to the extent that skin does. Advances in research over the past several decades have yielded a tremendous amount of information on the molecular pathways involved in both intrinsic aging (natural) and extrinsic aging (photoaging). In this article, we aim to describe the molecular pathways that lead to an aged appearance and to describe the latest and most commonly employed drugs and procedures to reverse skin aging and stimulate the production of new collagen. With enhanced understanding of these molecular pathways, drugs and devices used to treat aging skin can be more precisely tuned. Clinical Pharmacology & Therapeutics (2011) 89 1, 34–43. doi: 10.1038/clpt.2010.259