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How Informatics Can Potentiate Precompetitive Open‐Source Collaboration to Jump‐Start Drug Discovery and Development
Author(s) -
Perakslis E D,
Dam J,
Szalma S
Publication year - 2010
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.2010.21
Subject(s) - enthusiasm , open source , biopharmaceutical , informatics , translational research , translational medicine , productivity , drug discovery , clinical pharmacology , open innovation , computer science , data science , pharmacology , knowledge management , medicine , software , engineering , bioinformatics , psychology , microbiology and biotechnology , biology , social psychology , macroeconomics , pathology , electrical engineering , economics , programming language
Much enthusiasm and energy are being directed toward open‐source software approaches, precompetitive data sharing, and external innovation in the biopharmaceutical industry. At Johnson & Johnson (J&J), we have undertaken aggressive approaches to optimizing productivity and progress to address unmet medical needs. In this article, tranSMART, a fully translational data warehouse based on the open‐source i2b2 platform, serves as a case study and the basis for discussing the positive role that informatics can play in accelerating translational research. Clinical Pharmacology & Therapeutics (2010) 87 5, 614–616. doi: 10.1038/clpt.2010.21