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Communicating Pharmacogenetic Research Results to Breastfeeding Mothers Taking Codeine: A Pilot Study of Perceptions and Benefits
Author(s) -
Madadi P,
Joly Y,
Avard D,
Chitayat D C,
Smith M A,
Ross C J D,
Carleton B C,
Hayden M R,
Koren G
Publication year - 2010
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.2010.125
Subject(s) - breastfeeding , codeine , pharmacogenetics , medicine , perception , psychology , family medicine , environmental health , anesthesia , pediatrics , genotype , biochemistry , chemistry , morphine , neuroscience , gene
Sixty‐two codeine‐prescribed breastfeeding mothers from a pharmacogenetic study were interviewed regarding the communication of individual CYP2D6 genotype results and overall research findings. All participants wanted to receive the results of their individual genetic tests; however, individuals placed different values on the usefulness of this information toward future medical decisions. Receiving one's pharmacogenetic test results was not associated with a negative psychosocial impact. Thirty‐three percent of the participants wished to withhold these results from their physicians. Participants' expectations seem to dictate the extent of transparency of pharmacogenetic research results. Clinical Pharmacology & Therapeutics (2010) 88 6, 792–795. doi: 10.1038/clpt.2010.125