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The Next Generation of Drug‐Delivery Microdevices
Author(s) -
Elman NM,
Patta Y,
Scott AW,
Masi B,
Ho Duc HL,
Cima MJ
Publication year - 2009
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.2009.4
Subject(s) - drug delivery , nanotechnology , medicine , drug , miniaturization , clinical pharmacology , pharmacology , computer science , biomedical engineering , materials science
Advances in microelectromechanical systems (MEMS) and miniaturization technologies have enabled the creation of biomedical microdevices intended for use in the treatment of various chronic and acute illnesses. The ability to create very precisely defined micrometer and nanometer features allows for the production of a new generation of biomedical devices that can be implanted using minimally invasive procedures to provide controlled therapeutic drug delivery. We believe that there is a wide variety of pharmacological therapies in which these novel drug‐delivery systems could be implemented, including treatments for cancer and trauma. Clinical Pharmacology & Therapeutics (2009); 85 , 5, 544–547 doi: 10.1038/clpt.2009.4