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Evidence‐Based Antimicrobial Therapy in Pregnancy: Long Overdue
Author(s) -
Theiler R N
Publication year - 2009
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.2009.123
Subject(s) - clinical pharmacology , intensive care medicine , medicine , clinical trial , pregnancy , antimicrobial , drug , pharmacotherapy , pharmacology , psychiatry , biology , genetics , microbiology and biotechnology
Little evidence exists to guide the clinician caring for pregnant patients with infectious morbidities. The already‐small pool of evidence shrinks rapidly as the pathogen becomes more exotic, making therapeutic decisions increasingly speculative when emerging infectious diseases appear in the pregnant patient. The current drug approval mechanisms, legal environment, and profit‐driven drug pipeline have combined to exclude pregnant women from clinical trials, paradoxically resulting in a dangerous situation for pregnant women around the world. Clinical Pharmacology & Therapeutics (2009); 86 3, 237–238. doi: 10.1038/clpt.2009.123