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Optical Molecular Imaging: From Single Cell to Patient
Author(s) -
Moriyama EH,
Zheng G,
Wilson BC
Publication year - 2008
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.2008.58
Subject(s) - molecular imaging , drug discovery , nanotechnology , clinical pharmacology , optical imaging , computer science , computational biology , drug delivery , drug development , medical physics , drug , data science , medicine , bioinformatics , pharmacology , biology , microbiology and biotechnology , materials science , physics , in vivo , optics
Optical imaging is an emerging field with a wide range of biomedical research and clinical applications, both current and future. It comprises several classes of techniques that are capable of providing information at the molecular, cellular, tissue, and whole‐animal levels. These techniques match well with emerging genomic and proteomic technologies that enable development of optical “probes,” as well as with nanotechnologies for multifunctional imaging and drug delivery. These advances have enormous potential to accelerate drug discovery/development by providing predictive information on mechanisms of action and biological responses. Clinical Pharmacology & Therapeutics (2008); 84 , 2, 267–271 doi: 10.1038/clpt.2008.58